This Fuels Cancer Growth — And It’s in Your Daily Diet

[Music] you you have you've obviously copious amounts of of publications and some of your publications talk about uh cancer as a metabolic disease and specifically a a dysfunction of the mitochondria. Can you can you talk a bit about that? Yeah. So, um I mean this goes back to the work of Otto Warberg uh in the 1920s and 30s and 40s where he defined that cancer originated from damage to um mitochondria uh and that then elicited a whole series of changes uh forcing the cell into a fermentation mechanism to survive. um and and we we have uh validated and confirmed Warberg's original finding. So in order to do that uh what I did uh was to go through the through the lit the scientific literature looking looking at um electron mic microraphs the very high um magnification uh of m of mitochondria and tissues because you can't see them under light microscopic microscopy. In order to look at the structure of the mitochondria in the cytoplasm of the cell, you need you really need electron um electron microscopy scanning electron microscopy. And then when you look at so what I did is I went and I looked at all the major cancers probably representing 95% of all uh cancer deaths caused by by these kinds of cancers. And in and I went back through the 50s and 60 1950s,60s7s because in a lot of uh medical schools uh people would be looking at cancer tissue with electron microscopy and then you go to those papers and and you look and see what they found with respect to the the number and structure of the mitochondria in those tissues. And invariably they were abnormal structurally and even in even if one were to isolate them and look at the biochemistry it was abnormal. Um so we have never found normal mitochondria in any kind of a major cancer. Okay. So if you don't have normal mitochondria that means the cells are not going to be able to generate energy through normal respiratory systems like oxidative phosphorilation. And this is exactly what Warberg said. He said mitochondria oxidative phosphorilation becomes irreversibly damaged in all cancers regardless of where they come from thereby forcing them into a fermentation mechanism. And that's what the characteristics of all cancer cells are. They ferment and and then what we did is what we did is we well Warberg knew glucose was the lactic acid fermentation derived from glucose was the major fuel at that time. We have now defined uh glutamine a as a second fermentable fuel. The field had think thought for many years that glutamine was being respired. No, it's not respired. It's fermented. So the two fermentation fuels that drive the majority if not all cancers are a a sugar fermentation and an amino acid fermentation. And without the glucose and glutamine, no cancer cell can survive. So our our goal is to scientifically validate fermentation uh mechanism for glutamine and uh and show how Warberg was right uh on his original description, but he also did not have new information which would clarify and sol and and resolve this entire cancer issue. And we're in the process of doing this right now. Yeah, that's fantastic. And and so what what are some of the things that you that can disrupt the mitochondria to make them precipitate cancer? And how does that how does that go about? You know, I've seen, you know, some you talk you talk about how this actually precipitates the genetic uh mutations that we see and attribute blame to as causitive. Um but you're saying that that's actually a knock-on effect. Yeah, it's so they're all the mutations are all downstream of phenomena as as are most of what people are studying today. um are all downstream. The angioenesis, the failure in apoptosis and all these kinds of things, they're all downstream of the original damage to the mitochondria. So to answer specifically your question, it's called the ankcogenic paradox. And this paradox has uh perplexed the cancer field for decades. In other words, um, how is it possible that you could get cancer from a whole range of different kind of insults? How what is a what is the common pathophysiological mechanism that could underly this uh range of cancer initiators? Um, like for example, some people u women may get breast cancer from a clogged milk duct. Another one may get it from some sort of viral infection. Another one may get it from a unhealed wound. There's a whole variety of different ways that could elicit elicit a breast cancer. You can do the same thing. You can consider the same thing for possible colon cancers um or bladder cancers or lung cancers or any of these kinds of things. In other words, there's not any one uh, of course, smoking uh would damage uh the mitochondria in certain uh lung tissues and possibly other tissues. intermittent hypoxia, you know, uh radiation, um chronic inflammation, any any of these kinds of insults could damage a cell in a particular tissue, damage the mitochondria of a cell in a particular tissue leading to disregulated cell growth in that tissue. And the definition of cancer is cell division out of control or disregulated cell growth. How does that happen? It happens from damage to the mitochondria in a particular cell or populations of cells in a particular tissue eliciting a growth uh a disregulated growth and that's the encogenic paradox. So you don't always get cancer from a single insult. It could come from a variety of insults. The bottom line is that you end up with cells that are disregulated in their cell growth. All of which are fermenting. Um and it's important to rec recognize that the mitochondria of our cells is the controller of the cell cycle. So when that organel becomes defective, the cell falls back into a a disregulated cycle leading to and this is the way all cells uh on the planet uh evolved before oxygen came into the atmosphere 2.5 billion years ago. We had living cells on the planet before oxygen was in the atmosphere and they were all fermenting and they all had disregulated cell growth. So the cancer cells in bodies are simply falling back on these ancient pathways that have always existed even before respiration, even before the origination of the mitochondria. So the cells are just simply falling back. And as long as they have fermentable fuels in the environment, they're very difficult to kill. radiation and chemo and all these things that we use are not at the heart of the problem. And as a matter of fact, some of the standards of care actually facilitate the availability of fermentable fuels, making the the management of the disease impossible. So that's why the current standard of care makes no sense when one considers the origin of the disease in the concepts of evolutionary biology. Hey everyone, really happy to announce a new sponsor for the show for everybody down in Australia. It's Stockman Steaks, who are delivering high quality grass-fed and finished pasture-raised beef and other meats flash frozen and vacuum sealed to your door. Something I've been enjoying a lot of myself recently as well. They also have a great range of specialty items such as highfat keto mints and carnivore beef and organs mints with liver, kidneys, and beef heart as well. So, use code chaffy today for a free order of beef mints or another specialty gift along with your order at stockmanstakess.com.au and I'll see you over there. Thanks, guys. Yeah. Um I I did read a study, you know, a number of years ago where it spoke about you when people go into a ketogenic diet and it's speaking specifically about using ketosis in order to buy cancer and and talking about mitochondria specifically and showing that when in a state of ketosis you actually your mitochondria first of all uh were more efficient and they also increased in number and so you know and it's this uh sort of mechanism that uh uh would would protect from cancer. Um, what is it about eating carbo carbohydrates and not being in ketosis that just jams up our our mitochondria so much? Well, I don't I don't think the carbohydrates u jam up the mitochondria. Mhm. Um what what happens is uh excessive amounts of carbohydrates facilitate the um it causes an inflammatory situ condition in the body and it's this it's this elevated uh inflammation the state of an inflammation um that uh uh contributes to the damage. So you know sugar itself is not a carcinogen. However, uh chronic consumption of excessive carbohydrates can put the body in an imbalanced nutritional state and that's what elicits. It's not only cancer, it's type two diabetes. It's Alzheimer's disease. It's cardiovascular disease. Essentially, it's all of the major chronic diseases that we are currently suffering from is the result of excessive amounts of carbohydrates in the diet. We as a species did not evolve to eat uh large amounts of carbohydrates. It was only a seasonal kind of situation. A a ripe fruit, a ripe berry, or something like this would be the sweet, maybe honey. It wasn't chronic exposure to high levels of carbohydrates that are coming from the foods that we presently have in our societies. And that is al ultimately the origin of the majority of chronic diseases that we have is a a diet that is does not fit our evolutionary past. Yeah, I 100% agree with you on that and and that's something that I've sort of argued for a while now, which is that, you know, the chronic diseases that we're we're treating nowadays, you know, exactly as you've outlined, are are not diseases per se, but you know, toxicities and malnutrition to toxic buildup of species in appropriate diet and a lack of species specific nutrition and and you build up these toxins. As I sort of mentioned to you before um before we started filming, you know, I I got into this by when I took cancer biology and we talked about all carcinogens. You at the time, this was 20 years ago. There was uh we were told about there was 136 known carcinogens just in Brussels sprouts and over 100 in mushrooms and so on. So uh you know plants obviously using defense chemicals to stop predation or deter predation. This can build up and cause these these uh toxic effects in our body. And uh well well let me say that I I think that's true for the industrially produced vegetables. I think uh organic vegetables if one were to use natural fertilizers you know um you know uh as as would be as would be appropriate. I think you can reduce significantly but the problem is the um organic foods are hard to come by. There's no known it's not known whether they're really organic or not. Yeah. Um I I I don't think there's any regulatory commission um you know of freerange animals or organic plants. I mean this is what we evolved to eat. They were all organic you know 50,000 years ago. There was no industrial harvesting of foods. Um but I but I but I think that uh organically grown um um vegetables if one could do that uh um you know with natural fertilizers I think those would be very very healthy along with any other uh freerange uh of meat products or things like this. The problem is they're not convenient for the majority of people in the society. you know, a drive up McDonald's hamburger is a hell of a lot easier than going out and shooting a deer in the woods. Yeah. You know, um it's just the way our society is. Um and and our demands on our time and what we do uh prevent us from actually rebalancing our our our physiology, but yet we put ourselves at risk for cancer and all these other chronic diseases by the convenience of our lifestyle. Yeah. Yeah. No, and I certainly agree like any any sort of, you know, whole foods approach, you're going to be in much better uh stead. Um, you know, one of the things that that uh you we went through was actually a guy from uh Berkeley, Professor Bruce Ames, and he published in 1989 uh some work looking at comparison to AAR, which was a a pesticide used on apples at the time. They were trying to ban it. And he actually showed that uh he was looking specifically in mushrooms that that mushrooms had around 10,000 times the amount of natural insecticides and pesticides by weight uh as as the aar would get pumped on these plants and that it was it was more likely to cause cancer than natural ones as well. Um but yeah 100% you know obviously you know um pesticides insecticides these are toxic by design. they're trying to to, you know, kill insects from eating them. And so certainly that's going to make things a lot worse. And well, we we we in my book I showed that a lot of these so carcinogens that you just mentioned, they're they're taken up in mamalian cells and uh they actually cause the mitochondria to flues. They call bio biofllororescent. So you can you know there those carcinogens are going right to the mitochondria and uh and damaging the mitochondria which is then the first step the first step in the initiation of cancer is to disrupt oxidative phosphorilation and only cells that can upregulate a fermentation mechanism as the result of this damage can become cancer cells. Cells that cannot upregulate fermentation rarely if ever become tumorogenic. cells of cardiomyioittes they can't switch from oxfos to fermentation. Neurons in the brain rarely become tumorogenic. It's the gal cells not the neuron. Neurons can't ferment for very long. So only cells that have the capacity to replace respiration with fermentation can become a cancer cell. Otherwise you you can't do that. Oh that's very interesting and I think that's that's a good uh illustration of of what the actual mechanism is going on as well. Yeah. I mean it becomes very clear once you understand the biology of the problem um uh understanding how we how we get it and more importantly understanding how we manage it uh becomes very logical. The problem is this information is not known by the majority of oncologists or scientists in the field. Absolutely. And um you know I'm just that that you know with with my sort of endeavors into into nutrition and how this affects uh disease you know even even just the idea that that uh you know diabetes and heart disease um are are you know caused by sort of eating eating a lot of carbohydrates and sugar and all these sort of things. A lot of people uh really don't know that like doctors and nutritionists as well and they still sort of are on the same you know cholesterol will kill you sort of idea which I think has been thoroughly debunked. Hey guys, just want to take a second to thank our sponsor Carnivore Bar. 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Um you're you're absolutely right you know and and in the cancer wards they still give the cancer patients you know uh sugar and coke and ice cream cake. Um and then they say glucose has nothing to do with cancer. So there's there's such a lack of knowledge that it's profound. It's it's chasmic. It's unbelievable the lack of knowledge on the part of the health care industry as to what what should and should not be done to keep people healthy. Yeah, that that's one of the things, you know, I I sort of was, you know, was a bit upset there because I see this every day in the hospital. You know, I see the food that they they feed them. It's just it's just sugary carbs. That's it. And there's almost no meat. There's certainly no fat. Uh there's a bit of dairy, but it's it's always like chocolate milk as opposed to just normal milk. and and the rest of it is just is just garbage. And I'm I'm going around seeing our brain tumor patients and who just underwent uh surgery and and here they are eating all this this sugary nonsense. And I just can't help but think I mean like this is this is what gave you this problem in the first place and and we're just shoveling it into your face. Yeah. It drives it drives the tumor. And and what we also found um I published a major paper on this uh with the standard of care for for brain cancer um the very treatments that are used the um uh radiation as well as teosolomide um they free up massive amounts of glucose and glutamine in the tumor micro environment uh making long-term survival very very rare. So it's the therapies themselves that in other words that's bad enough to have a glyobblasto. It's even worse to use standard of care to treat it because you've more or less signed and sealed the death certificate of this patient um simply by the the human brain should rarely if ever be irdiated. This is nonsense. This has to stop people. I published a clear paper on how the radiation breaks apart the glutamine glutamate cycle in the brain freeing up massive amounts of glutamine and the and the uh steroids they give these patients increases blood sugar. The two fuels necessary for causing cancer cells to grow out of control are made available in abundant quantities by the very treatments that we're doing uh to these patients. Yeah. So um we have made no advance in glyobblasto therapy in almost 100 years and my most recent paper shows in 100 years we have a telescope that now orbits 1 million miles from earth to look at the very origins of our solar system. um uh this new telescope. I can't remember the name of it, but but anyway, and yet and yet we do that and we've made no no advance in glyopblasto. Yeah. So, so and many other cancers. Once you have metastatic lung cancer, a colon cancer, the the survival is is so much less because the treatments we're using contribute to the demise of these patients. It's unbelievable. Yeah. Absolutely. It's a tragedy. It's actually a tragedy. Yeah. and and and you know chemo can be so hard on people and you know I don't I don't know what people are more concerned with like getting cancer or getting cancer and realizing that means they need chemo because you know I've had I've had friends and obviously patients devastated by by these treatments. Yeah. I think they fear the treatment as much as they do the disease. They don't they think their hair is going to fall out. They're going to bleed from the gums. They're going to be sick and tired all the time. you know, many people are some people recover really well. Actually, um there are some reports now that show water only therapeutic fasting can significantly reduce some of the toxic effects of chemotherapy. But my my my point is why would you want to use chemotherapy when we know we just have to pull the plug on the fermentable fuels with diet and very and drugs that aren't not are not so toxic especially when under therapeutic ketosis. I mean there's a clear framework and strategy for managing cancer without toxicity. The biggest problem is no business model to support this which is the singular greatest st uh inhibitor of moving this forward. There is no way yet that people have found out how to make money uh on metabolic therapy. That's the biggest problem. Not the it's not the patient that should be benefited. It's how to make revenue from this. I think the entrepreneur will come and the entrepreneur will figure out how to do this. I'm not that kind of a person. My job is not how do we keep cancer patients alive with a higher quality of life beyond what they were ever predicted to to have. They're all very very prone. They all have to ferment. So um you know and blood can all the blood cancers are all driven by glutamine. They're in the blood you know. So so you're you're you're talking about all the major cancers. You know here's the situation. There are reports in the scientific literature.