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16:47 · Mar 01, 2025

Is LDL Cholesterol Really The Bad Guy?

Dr. Anthony Chaffee dismantles the cholesterol hypothesis by examining the flawed research behind it, particularly Ancel Keys' fraudulent Seven Countries Study. He explains that LDL cholesterol is actually a beneficial transport molecule that increases during fasting and fat adaptation, making it unlikely to cause harm. The episode reveals how the sugar industry funded biased research to blame saturated fat instead of sugar for heart disease.

Listeners learn about the biological differences between human cholesterol and plant sterols, which cannot be properly utilized by the body and may accumulate in arterial plaques. Dr. Anthony Chaffee addresses specific concerns about high blood pressure on carnivore diets, explaining that elevated insulin, homocysteine, and sometimes salt sensitivity are the real culprits. He emphasizes that optimal nutrition for any species - including the carnivore diet for humans - remains beneficial under all circumstances.

Key Takeaways

  • LDL cholesterol increases naturally during fasting and fat adaptation as a transport mechanism, with randomized controlled trials showing more people died when LDL was lowered using vegetable oils instead of animal fats
  • Plant sterols from seed oils lower cholesterol readings but cannot be used by cells to make hormones or vitamin D, leading to accumulation in arterial plaques unlike human cholesterol
  • High blood pressure on carnivore diets often improves by reducing insulin and homocysteine levels, though some individuals may need to monitor salt sensitivity and work with doctors to adjust medications
  • Ancel Keys' Seven Countries Study was fraudulent - he had data on 22 countries but cherry-picked 7 that supported his hypothesis, while sugar consumption showed identical correlation patterns to cholesterol
  • LDL Cholesterol and Heart Disease - Debunking the Myth
  • Plant Sterols vs Animal Cholesterol - Why Your Body Needs the Real Thing
  • Ancel Keys Sugar Industry Fraud - The Seven Nations Study Deception
  • Carnivore Diet Benefits and Getting Started - Real Results from Real People
  • High Blood Pressure and Carnivore Diet - Managing Medication and Salt Sensitivity

This is an auto-generated transcript from YouTube and may contain errors or inaccuracies.

[Music] Mike says if LDL is okay um but may cause plaque if vessels are damaged by glucose as it tries to repair it um could a cerebral flow diverter um aneurysm and high LDL CA plaque carnivore okay if um flow diverter F do flow diverter fit it um I know don't I don't actually think that LDL is part of this process at all really I don't think that high I don't think that you need you need damage right um um you know but you you damage your vessels with glucose you can damage it with homocystine you can damage it with nicotine you know it's sort of weird I think I think the tobacco companies are up up to their old tricks again you know putting out all this research about how great nicotine is is for you uh nicotine suck nicotine is a drug nicotine causes direct damage to your body and your brain and your vasculature it causes um it actually can damage the arterial lining of your of your vessels and U and that that starts the process for atherosclerosis right and periperal vascular disease and and these sorts of things right so um not what you want um so uh but it's it's it's more than just glucose so you know the question is um you know LDL is okay but may cause plaque if the vessels are damaged I don't think that that's the case and I and there I don't think there's any evidence to show that in fact there is no evidence to show that higher levels of LDL do not correspond with higher levels of cardiovascular disease and the correlation is not causation in any case um but the only randomized control trials that we have on the sub object and people oh well that's not a good Stu they're the only ones we have so you don't like it do a better one right but um they're the only ones we have and the only ones we have show that in randomized control trials with thousands of patients that when you reduce LDL and replace saturated fat with polyunsaturated you know vegetable oils and Seed oils that uh more people die of heart attacks and strokes as a result so this is just not something that we can actually even suggest that cholesterol is is part of this you know in fact there are studies looking at um seed oils that have you know plant oil plant fats have have steriles which is the plant version of cholesterol we don't need the plant versions of things we need the animal versions of things and the plant versions of cholesterol will lower our cholesterol because it it sends a signal to our liver that we're getting cholesterol in from our food and so we don't need to make as much fine um um but it's not actually cholesterol we don't actually use it cholesterol we can't use it properly as as a building um material and structural component we can't use it for to make our hormones or vitamin D Etc which is what all our hormones vitamin D are made of is cholesterol and so it actually screws things up a lot and also macras is really like cholesterol they hang on to it tightly all cells make cholesterol and um so they really like human cholesterol they don't like plant stero and so they actually spit those out very readily and um and so they've actually found in like AAA um you know on histology on Triple H which which in um abdominal ortic aneurysm that uh they actually found this stuff stuffed in these all these plant sterols and we also know that they know like trans fats these things are very atherogenic right so these cause a lot of a lot of these plaques these are fats that just our bodies just have no idea what to do with because trans fats don't exist in nature right so that that's something our bodies have never seen before our bodies don't know what the hell to do with it they end up getting stuffed into weird places that shouldn't really be there and cause problems like cardiovascular disease and um so that's what's happening I don't think for a cold Frozen second that um that our own um that our own cholesterol is doing that LDL is just a carrier molecule it carries cholesterol it carries uh lipids and it carries proteins so does HDL HDL just carries slightly less cholesterol very similar molecules so just having more LDL molecules why why would that cause a problem you know when you fast you just stop eating for five days your LDL will go up right because you're actually you're running on your fat stores it's a metabolic State chain you're running on your fat stores and so you need to transport that fat lipids and cholesterol proteins Etc you need to transport that around the body so you need more of these things as part of fat adaptation is getting more LDL more HDL right is because you need to transport this around the body you start eating carbohydrates that goes right down you start exercising it goes up right because you're you're need more energy you're trying to mobilize things right so fasting regular periods of time um that's been shown to improve health in a number of different ways right including heart disease risk and and things like that and so but it raises your LDL if LDL directly causes harm what's going on right hey everyone really happy to announce a new sponsor for the show for everybody down in Australia Stockman staks who are delivering highquality grass-fed and finished pasture raised beef and other meats flash frozen and vacuum seal to Door something I've been enjoying a lot of myself recently as well they also have a great range of specialty items it such as high fat keto mints and carnivore beef and organs mints with liver kidneys and beef heart as well so use code chafy today for free order of beef mints or another specialty gift along with your order at Stockman steaks.com Au and I'll see you over there thanks guys um so again it's just like it doesn't make sense it doesn't pass the smell test it was made up in the first place you know there it wasn't group of serious scientists are like oo we really think this is what's going on it was a sugar companies in the first place and probably the to companies along with them pushing this narrative and making up this story and paying off people like anel keys and professors from Harvard and elsewhere to just and lie and and make up studies and and things like that anel Keys was um you know did the Seven Nation study that was a garbage study he completely falsified all sorts of different data you know he had R value for his Seven Nations or were 22 Nations he had complete data on he just completely omitted those and so he just the ones that that fit that graph that said oh more cholesterol more heart disease you know the interesting thing there if you just looked at Sugar consumption as well it had the exact same curve for those exact same countries so was called an R value so your relative risk Association for cholesterol was exactly the same as relative risk association with sugar consumption and guess what anel Keys's take-home was from that study and the rest of his work was cholesterol could really be a problem eat sugar instead what kind of do you have to be to make that sort of statement so this guy this guy was uh this guy was a fraud and I I think his entire life's work should be burned to the ground I mean the guy you just can't trust a single word of it um other people think that you know he was just ideologically driven and and and you know really wanted the best but just couldn't couldn't accept that this went against his life work that happens too but I think that it's more like in my mind just being the cynical sort of person and that I am uh that that this was just he was just a fraud through and through um because it you know he was just paid from day one to just push this narrative you know and um and he had the data in front of him I mean he he had the r value for sugar was exactly the same as the R value for cholesterol and yet he recommended you just cut out fat and replace that with sugar because sugar is an empty calorie you know you need these calories from somewhere so just replace them with sugar and he was being paid by the sugar companies so I I don't I don't think that he was being honest by any stretch of the imagination and then he actually worked on one of these large scale randomized control trials um called the Minnesota coronary experiment went for on for five years they looked at nearly 10,000 uh people that were institutionalized in um psychiatric facil ities or uh the prison systems um prison and jail systems and and they didn't even know it was a double blinded study so you know they just replaced like butter with margarine and animal fats with with seed oils and uh and no one knew which group was which and the group that um had you know plant oils and margarin replaced for for animal fats did indeed reduce their cholesterol because of the plant sterols and more of them died of heart attacks and strokes as a result so what are we trying to what are we trying to accomplish here and and as a result Anil Keys refused to study the refused to publish the study and buried it so I mean this is like this is knowled this is this is malice of forethought this guy knows what he's doing so it's never been proven one way or the other that LDL is even associated with um with cardiovascular disease certainly has not been shown with randomized control trials and so I I just don't think we play into their game I don't well if we assum no we don't assume a thing make them prove it they have not proven it it's been disproven a number of times so I I just I don't accept that um that position at all and so you know I don't think that we need to even entertain this whole what if scenario because it's just it's it's a it's it's not likely to be um the case so carnivore diet is okay no matter what you do with you know so all of that scenario LDL and this and that and and all that carnivore is good carnivore is what your body's designed for your optimal nutrition for know carnivore diet for a lion is good under all any and all circumstances you know the grasses that cows and horses eat are optimal under any and all circumstances um you know so just the optimal nutrition for a species is always optimal for that species always right and um so you know I I wouldn't I wouldn't worry about this sort of thing and I don't worry about that sort of thing you watch my videos on the truth about cholesterol and heart disease you can watch um Dr Paul Mason's video he has multiple videos and lectures at medical conferences on on cholesterol saturated fat all these other sorts of things there's books uh written on the subject one's from uh Dr Malcolm Kendrick called the clot thickens goes through all this sort of stuff and talks about his his um idea about what really causing it and so on and so on and so on so um I I I just do not accept the premise that LDL has anything to do with cardiovascular disease uh if in in any way shape or form a part from being protective against it and um you know prove me wrong but right now the evidence shows uh is is entirely against that theory hey guys just want to take a second to thank our sponsor at carnivore bar I don't promote many products because honestly all you need to be healthy is to just eat meat for those times that you're out hiking road tripping or stuck at work and you want nutritious snack that is just meat fat and salt if you want it the carnivore bar is a great option so I like this product not because it's just pure meat but also because I want the carnivore Market to thrive as well and the more we support meat only products the more meat only product that will be available in the mainstream so if this sounds like something you'd like to get behind check it out using my discount code Anthony to get 10% off which also applies to subscriptions giving you 25% off total all right thanks guys Daniela tarantello thank you so much for the very generous Super Chat very kind of you uh thank you Dr chaffy love your passions and contributions uh I'm super inspired and grateful you're here in Australia started my carnivore Journey one a week ago well that's fantastic um that's that's really great to hear that Dani thank you very much for sharing that um and good luck with that you know the first couple weeks are a bit of a transition period some people feel really good I just felt great right away on it but after two weeks I really just the the improvements I saw in my health and my athletic performance just really just went through the roof I I I just couldn't believe how good I felt I felt better than than I had in my whole life except for that five-year period in my early 20s when I was inadvertently doing a cornivore diet because I just refused to eat any and all plants uh because my professor of um cancer biology told us how toxic they were and how carcinogenic they were you know when you have a professor of cancer biology um tell you uh that he doesn't eat any sort of plants vegetables or fruits grains because of how carcinogenic they are like you know that that sticks with you at least it stuck with me anyway so um you know now I'm doing this and I just feel amazing so uh hopefully you do as well and uh in the coming weeks I'm sure you'll feel better than you have in a very long time so good luck with that and um yeah thank you very much for for thinking about it and being open-minded enough to give something new a try uh ground Rush Labs thank you very much for the Super Chat uh question doc does line diet help with high blood pressure and rain out um so yeah so actually um if you if you roll back one of the first questions I answered was actually about high blood pressure the short answer is yes it can definitely help with a lot of causes of high blood pressure there are other causes but um many of them are high insulin high homocystine and sometimes salt but not always it's uh but I do I have seen that um even when people have corrected everything else salt can still be an issue so you just just be aware most people are not salt sensitive some people are so you need to be keep that in mind as well so um you know getting your insulin down getting your homosysteine down by getting your B12 up Etc um that can all help blood pressure over time you need to be very careful because if your blood pressure goes too low you can start getting dizzy and lightheaded and that that's a risk for Falls and so you need to be able to work with your doctor to um reduce your dose as needed especially if you're standing up you're sort of getting laded often um check your blood pressure it's it's probably because you're on too much medication at that point but do go back to the beginning of of this video I I go into a lot more detail about that but that's the that's the gist of it anyway um Annabelle the happy carnivore says I lose weight every time I eat fat trimmings that's really good um you know a lot of people find that as well you know when when you're eating properly it stimulates your metabolism it stimulates your body to just actually use its resources properly and and people you know lose quite a lot of weight and and some people actually get through stalls by increasing the amount of fat that they're eating which seems counterintuitive but I mean there's even books on this there was a there was a um there's a book in the 1950s from a doctor it was called eat fat to get thin and it was it was all about this say actually you need to eat get these things you need to eat your proper diet and um and by doing that you'll actually stimulate fat loss so glad to hear that you're that you're finding those same results have any autoimmune issues I don't have any specific health issues that I um have have to deal with I just feel better in general so I just naturally gravitate uh there anyway um but yeah if you find that you're doing better um with a bit of other other things mixed in that could be a reason why and either way if that's what you feel the best then do that
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